Why Was Silcrete Heat-Treated in the Middle Stone Age? An Early Transformative Technology in the Context of Raw Material Use at Mertenhof Rock Shelter, South Africa.

People heat treated silcrete during the Middle Stone Age (MSA) in southern Africa but the spatial and temporal variability of this practice remains poorly documented.This paucity of data in turn makes it difficult to interrogate the motive factors underlying the application of this technique.In this paper we present data on heat treatment of silcre

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LINE AND POLYGON TOPOLOGY IN OPENDRIVE MODELLING

The paper discusses the importance of efficient methods in the automotive industry for the development of self-driving vehicles Hog Rings and advanced vehicle assistants, focusing on the use of high-definition (HD) maps.The integration of computer simulation and HD maps in the OpenDRIVE format is emphasized.A paradigm shift in map topology is highl

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Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis

Abstract Background IgG4-related cholangitis (IgG4-SC) and primary sclerosing cholangitis (PSC) are chronic fibro-inflammatory hepatobiliary conditions, with genetic, environmental, and immunologic risk factors, in which epigenetic alterations may provide insights into pathophysiology and novel biomarkers.This study is the first to assess methylati

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